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Glavoboli povezani s temperaturo in nižjim zračnim tlakom

 
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Pridružen/-a: 11.09. 2008, 06:27
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PrispevekObjavljeno: 10 Mar 2009 08:26    Naslov sporočila: Glavoboli povezani s temperaturo in nižjim zračnim tlakom Odgovori s citatom

Višje temperature in v manjši meri zračni tlak prispevajo k hudim glavobolom

V študiji pri več kot 7000 bolnikih, ki so jih vodili raziskovalci na Beth Israel Deaconess Medical Center (BIDMC), je pokazala nekatere izmed prvih obsežnejših podatkov o tem, kako okoljski pogoji (vreme, kot tudi onesnaževanje zraka) vplivajo na glavobolne bolečine


Reported in the March 10 issue of the journal Neurology, the findings demonstrate that higher temperatures, and to a lesser degree, lower barometric pressure, contribute to severe headaches.
"Migraine headaches affect a large proportion of the population," notes Kenneth Mukamal, MD, MPH, the study's first author and a physician in the Division of General Medicine and Primary Care at BIDMC. "Approximately 18 percent of women and 6 percent of men in the U.S. report having migraine headaches, particularly young and middle-aged adults."
Knowing that migraines can be set off by "triggers," including certain foods, alcohol, stress and hormones, Mukamal and his coauthors decided to study whether environmental factors were also acting as headache triggers.
"Air temperature, humidity and barometric pressure are among the most frequent reasons that people give for their headache pain," explains Mukamal, who is also an Associate Professor of Medicine at Harvard Medical School. "But none of these reasons have been consistently verified. We wanted to find out if we could verify this 'clinical folklore.' We also wanted to determine whether air pollutants trigger headaches, much as they have been found to trigger strokes."
Mukamal and his coauthors designed a "case crossover" study, which directly compares levels of pollutants and meterological variables at the time of the patient's hospital visit with corresponding levels on preceding days and subsequent weeks. The study looked at 7,054 patients who went to the emergency room of Beth Israel Deaconess Medical Center between May 2000 and December 2007 and were discharged with a primary diagnosis of headache (2,250 diagnosed with migraine; 4,803 diagnosed with tension or unspecified headache). Using meterological and pollutant monitors, they then compared measurements of a number of environmental factors – air temperature, barometric pressure, humidity, fine particulate matter, black carbon, and nitrogen and sulfur dioxides -- during the three days previous to patients' hospital visits and then again at corresponding dates to determine whether these factors trigger severe headaches.
"In other words," says Mukamal, "our study design was able to directly compare weather and air pollution conditions right before an emergency visit with those same factors measured earlier and later the same month."
The findings showed that of all of the environmental factors considered, higher air temperature in the 24 hours prior to the patient's hospital visit was most closely associated with headache symptoms, with a 7.5 percent higher risk of severe headache reported for each temperature increase of 5 degrees Celsius (approximately 9 degrees Fahrenheit). To a lesser degree, lower barometric pressure 48 to 72 hours prior to patients' emergency room visits also appeared to trigger headache. The researchers found no evidence that air pollutants influenced the onset of headache, but could not rule out a smaller effect similar to that previously seen for stroke.
"Certainly our results are consistent with the idea that severe headaches can be triggered by external factors," says Mukamal. "These findings help tell us that the environment around us does affect our health and, in terms of headaches, may be impacting many, many people on a daily basis."
Mukamal recommends that headache patients sit down with their doctors to identify the triggers that lead to their headache symptoms, adding that even though the weather can't be altered, doctors might be able to prescribe medication that can be administered prophylactically to help avert the onset of weather-related headaches.
Furthermore, he adds, "On a population basis, we need to be concerned about incremental temperature rises anyhow, and should advocate for responsible environmental management. The annual cost attributed to migraines is estimated at $17 billion, millions of people are adversely affected and the public health implications may be enormous."
This research was supported by grants from the National Institute of Environmental Health Sciences and the U.S. Environmental Protection Agency.
Study coauthors include BIDMC investigators Gregory A. Wellenius, ScD, and Murray A. Mittleman, MD, DrPH; and Helen H. Suh, ScD, of the Harvard School of Public Health.

Vir: Beth Israel Deaconess Medical Center (2009, March 10). Severe Headaches Associated With Higher Temperatures, Lower Barometric
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